Cellosaurus cell line HyCyte Hep-G2 hUBE2O_p.K689R_c.2066A>G cell line (CVCL

Cross-references
Cell line name	HyCyte Hep-G2 hUBE2O_p.K689R_c.2066A>G cell line
Synonyms	hUBE2O_p.K689R_c.2066A>G cell line
Accession	CVCL_F4JV
Resource Identification Initiative	To cite this cell line use: HyCyte Hep-G2 hUBE2O_p.K689R_c.2066A>G cell line (RRID:CVCL_F4JV)
Comments	Population: Caucasian. Doubling time: 60-72 hours (Hysigen=CGMU-M2207). Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations	Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line). Mutation; HGNC; HGNC:29554; UBE2O; Simple_edited; p.K689R (NM_022066.4:c.2066A>G); Zygosity=Homozygous (Hysigen=CGMU-M2207). Mutation; HGNC; HGNC:29554; UBE2O; Simple_edited; p.V690V (NM_022066.4:c.2070G>C); Zygosity=Homozygous; Note=Synonymous mutation (Hysigen=CGMU-M2207).
Disease	Hepatoblastoma (NCIt: C3728) Hepatoblastoma (ORDO: Orphanet_449)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0027 (Hep-G2)
Sex of cell	Male
Age at sampling	15Y
Category	Cancer cell line
Cell line collections (Providers)	Hysigen; CGMU-M2207
Entry history
Entry creation	25-Jun-2026
Last entry update	25-Jun-2026
Version number	1