Cellosaurus cell line HyCyte MEG-01 KO-hCST7 (CVCL

Cross-references
Cell line name	HyCyte MEG-01 KO-hCST7
Synonyms	hCST7 knockout MEG-01 cell line
Accession	CVCL_F4H4
Resource Identification Initiative	To cite this cell line use: HyCyte MEG-01 KO-hCST7 (RRID:CVCL_F4H4)
Comments	Population: Japanese. Doubling time: 36-48 hours (Hysigen=CGKO-M3515). Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:2479; CST7. Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations	Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 13 fused to ABL1 exon 2 (b2a2 transcript) (from parent cell line). Mutation; HGNC; HGNC:18318; ASXL1; Simple; p.Gly646Trpfs*12 (c.1934dupG); ClinVar=VCV000426927; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.His233del (c.697_699delCAC); Zygosity=Heterozygous (from parent cell line).
Disease	Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110) Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0425 (MEG-01)
Sex of cell	Male
Age at sampling	55Y
Category	Cancer cell line
Cell line collections (Providers)	Hysigen; CGKO-M3515
Entry history
Entry creation	25-Jun-2026
Last entry update	25-Jun-2026
Version number	1