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Cellosaurus HyCyte SW1990 KO-hPHGDH (CVCL_F4EZ)

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Cell line name HyCyte SW1990 KO-hPHGDH
Synonyms hPHGDH knockout SW1990 cell line
Accession CVCL_F4EZ
Resource Identification Initiative To cite this cell line use: HyCyte SW1990 KO-hPHGDH (RRID:CVCL_F4EZ)
Comments Population: Caucasian.
Doubling time: 48-60 hours (Hysigen=CGKO-M3338).
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:8923; PHGDH.
Derived from site: Metastatic; Spleen; UBERON=UBERON_0002106.
Cell type: Epithelial cell of pancreas; CL=CL_0000083.
Sequence variations
  • Mutation; HGNC; HGNC:27310; FLCN; Simple; p.Gln533Ter (c.1597C>T); ClinVar=VCV000096480; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro191del (c.569_571CTC[1]) (c.572_574delCTC); ClinVar=VCV000458551; Zygosity=Heterozygous (from parent cell line).
Disease Pancreatic adenocarcinoma (NCIt: C8294)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1723 (SW1990)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; CGKO-M3338
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1