ID   HyCyte SW1990 KO-hPHGDH
AC   CVCL_F4EZ
SY   hPHGDH knockout SW1990 cell line
DR   Hysigen; CGKO-M3338
CC   Population: Caucasian.
CC   Doubling time: 48-60 hours (Hysigen=CGKO-M3338).
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:8923; PHGDH.
CC   Sequence variation: Mutation; HGNC; HGNC:27310; FLCN; Simple; p.Gln533Ter (c.1597C>T); ClinVar=VCV000096480; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro191del (c.569_571CTC[1]) (c.572_574delCTC); ClinVar=VCV000458551; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: Metastatic; Spleen; UBERON=UBERON_0002106.
CC   Cell type: Epithelial cell of pancreas; CL=CL_0000083.
DI   NCIt; C8294; Pancreatic adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1723 ! SW1990
SX   Male
AG   56Y
CA   Cancer cell line
DT   Created: 25-06-26; Last updated: 25-06-26; Version: 1
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