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Cellosaurus 698357-238-R-J1-PDC (CVCL_F4DG)

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Cell line name 698357-238-R-J1-PDC
Accession CVCL_F4DG
Resource Identification Initiative To cite this cell line use: 698357-238-R-J1-PDC (RRID:CVCL_F4DG)
Comments Part of: NCI Patient-Derived Model Repository.
Population: Caucasian; Utah residents with ancestry from Northern and Western Europe.
Characteristics: tumorigenic in NOD/SCID/IL2RgammaNULL (NSG) mice.
Characteristics: Established from a patient-derived xenograft (PDX) in NOD/SCID/IL2RgammaNULL (NSG) mice.
Doubling time: 67 hours (NCI-PDMR=3700).
Microsatellite instability: Stable (MSS) (NCI-PDMR=3700).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Bone, right scapula; UBERON=UBERON_0006849.
Sequence variations
  • Mutation; HGNC; HGNC:7765; NF1; Simple; p.M2526Ifs*10 (c.7577_7578insA); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 0.9886 (NCI-PDMR=3700).
  • Mutation; HGNC; HGNC:12363; TSC2; Simple; p.X1690_splice (c.5068+27_5069-47del); Zygosity=Heterozygous; Note=Likely Oncogenic, variant allele frequency: 0.3208 (NCI-PDMR=3700).
HLA typing Source: NCI-PDMR=3700
Class I
HLA-AA*24:02,24:02
HLA-BB*35:02,35:02
HLA-CC*04:01,04:01
Disease Osteosarcoma (NCIt: C9145)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 56Y
Category Cancer cell line
STR profile Source(s): NCI-PDMR=3700

Markers:
AmelogeninX
CSF1PO10
D2S133819,20
D3S135816,17
D5S81811
D7S82010,11
D8S117911,14
D13S31712
D16S53911,13
D18S5118
D19S43314
D21S1128,29
FGA19,22
TH016
TPOX10,11
vWA16

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Cross-references
Cell line collections (Providers) NCI-PDMR; 3700
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1