ID   698357-238-R-J1-PDC
AC   CVCL_F4DG
DR   NCI-PDMR; 3700
CC   Part of: NCI Patient-Derived Model Repository.
CC   Population: Caucasian; Utah residents with ancestry from Northern and Western Europe.
CC   Characteristics: tumorigenic in NOD/SCID/IL2RgammaNULL (NSG) mice.
CC   Characteristics: Established from a patient-derived xenograft (PDX) in NOD/SCID/IL2RgammaNULL (NSG) mice.
CC   Doubling time: 67 hours (NCI-PDMR=3700).
CC   HLA typing: A*24:02,24:02; B*35:02,35:02; C*04:01,04:01 (NCI-PDMR=3700).
CC   Microsatellite instability: Stable (MSS) (NCI-PDMR=3700).
CC   Sequence variation: Mutation; HGNC; HGNC:7765; NF1; Simple; p.M2526Ifs*10 (c.7577_7578insA); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 0.9886 (NCI-PDMR=3700).
CC   Sequence variation: Mutation; HGNC; HGNC:12363; TSC2; Simple; p.X1690_splice (c.5068+27_5069-47del); Zygosity=Heterozygous; Note=Likely Oncogenic, variant allele frequency: 0.3208 (NCI-PDMR=3700).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: In situ; Bone, right scapula; UBERON=UBERON_0006849.
ST   Source(s): NCI-PDMR=3700
ST   Amelogenin: X
ST   CSF1PO: 10
ST   D13S317: 12
ST   D16S539: 11,13
ST   D18S51: 18
ST   D19S433: 14
ST   D21S11: 28,29
ST   D2S1338: 19,20
ST   D3S1358: 16,17
ST   D5S818: 11
ST   D7S820: 10,11
ST   D8S1179: 11,14
ST   FGA: 19,22
ST   TH01: 6
ST   TPOX: 10,11
ST   vWA: 16
DI   NCIt; C9145; Osteosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   56Y
CA   Cancer cell line
DT   Created: 25-06-26; Last updated: 25-06-26; Version: 1
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