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Cellosaurus 594176-295-R-J2-PDC (CVCL_F4DE)

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Cell line name 594176-295-R-J2-PDC
Accession CVCL_F4DE
Resource Identification Initiative To cite this cell line use: 594176-295-R-J2-PDC (RRID:CVCL_F4DE)
Comments Part of: NCI Patient-Derived Model Repository.
Population: Caucasian; Utah residents with ancestry from Northern and Western Europe.
Characteristics: tumorigenic in NOD/SCID/IL2RgammaNULL (NSG) mice.
Doubling time: 41 hours (NCI-PDMR=3117).
Microsatellite instability: Stable (MSS) (NCI-PDMR=3117).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Bone, right proximal humerus; UBERON=UBERON_0000976.
Sequence variations
  • Mutation; HGNC; HGNC:5382; IDH1; Simple; p.R132G (c.394C>G); Zygosity=Heterozygous; Note=Oncogenic, variant allele frequency: 0.6408 (NCI-PDMR=3117).
  • Mutation; HGNC; HGNC:9585; PTCH1; Simple; p.V763Gfs*27 (c.2282dup); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 1 (NCI-PDMR=3117).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.V172D (c.515T>A); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 1 (NCI-PDMR=3117).
HLA typing Source: NCI-PDMR=3117
Class I
HLA-AA*02:01,03:01
HLA-BB*57:01,58:01
HLA-CC*07:01,12:03
Disease Osteosarcoma (NCIt: C9145)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 72Y
Category Cancer cell line
STR profile Source(s): NCI-PDMR=3117

Markers:
AmelogeninX,Y
CSF1PO11,12
D2S133817,25
D3S135814
D5S8189,12
D7S82010
D8S117912
D13S31712
D16S5399,11
D18S5117,18
D19S43314,15
D21S1130,31.2
FGA20,25
TH019,9.3
TPOX8,11
vWA14,17

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Cross-references
Cell line collections (Providers) NCI-PDMR; 3117
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1