ID   594176-295-R-J2-PDC
AC   CVCL_F4DE
DR   NCI-PDMR; 3117
CC   Part of: NCI Patient-Derived Model Repository.
CC   Population: Caucasian; Utah residents with ancestry from Northern and Western Europe.
CC   Characteristics: tumorigenic in NOD/SCID/IL2RgammaNULL (NSG) mice.
CC   Doubling time: 41 hours (NCI-PDMR=3117).
CC   HLA typing: A*02:01,03:01; B*57:01,58:01; C*07:01,12:03 (NCI-PDMR=3117).
CC   Microsatellite instability: Stable (MSS) (NCI-PDMR=3117).
CC   Sequence variation: Mutation; HGNC; HGNC:5382; IDH1; Simple; p.R132G (c.394C>G); Zygosity=Heterozygous; Note=Oncogenic, variant allele frequency: 0.6408 (NCI-PDMR=3117).
CC   Sequence variation: Mutation; HGNC; HGNC:9585; PTCH1; Simple; p.V763Gfs*27 (c.2282dup); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 1 (NCI-PDMR=3117).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.V172D (c.515T>A); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 1 (NCI-PDMR=3117).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: In situ; Bone, right proximal humerus; UBERON=UBERON_0000976.
ST   Source(s): NCI-PDMR=3117
ST   Amelogenin: X,Y
ST   CSF1PO: 11,12
ST   D13S317: 12
ST   D16S539: 9,11
ST   D18S51: 17,18
ST   D19S433: 14,15
ST   D21S11: 30,31.2
ST   D2S1338: 17,25
ST   D3S1358: 14
ST   D5S818: 9,12
ST   D7S820: 10
ST   D8S1179: 12
ST   FGA: 20,25
ST   TH01: 9,9.3
ST   TPOX: 8,11
ST   vWA: 14,17
DI   NCIt; C9145; Osteosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   72Y
CA   Cancer cell line
DT   Created: 25-06-26; Last updated: 25-06-26; Version: 1
//