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Cellosaurus 589616-265-R-J2-PDC (CVCL_F4DD)

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Cell line name 589616-265-R-J2-PDC
Accession CVCL_F4DD
Resource Identification Initiative To cite this cell line use: 589616-265-R-J2-PDC (RRID:CVCL_F4DD)
Comments Part of: NCI Patient-Derived Model Repository.
Population: Caucasian; Utah residents with ancestry from Northern and Western Europe.
Characteristics: tumorigenic in NOD/SCID/IL2RgammaNULL (NSG) mice.
Characteristics: Established from a patient-derived xenograft (PDX) in NOD/SCID/IL2RgammaNULL (NSG) mice.
Doubling time: 53 hours (NCI-PDMR=12573).
Microsatellite instability: Stable (MSS) (NCI-PDMR=12573).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Left thigh; UBERON=UBERON_0000376.
Sequence variations
  • Mutation; HGNC; HGNC:3188; EED; Simple; p.X287_splice (c.861-1G>T); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 1 (NCI-PDMR=12573).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.P153Afs*28 (c.456dup); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 1 (NCI-PDMR=12573).
HLA typing Source: NCI-PDMR=12573
Class I
HLA-AA*02:01,30:01
HLA-BB*13:02,18:01
HLA-CC*06:02,07:01
Disease Malignant Peripheral Nerve Sheath Tumor (NCIt: C3798)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): NCI-PDMR=12573

Markers:
AmelogeninX,Y
CSF1PO11,13
D2S133818,22
D3S135817
D5S81812,13
D7S82010
D8S117910
D13S3178
D16S5399,13
D18S5115
D19S43313,14
D21S1127,31
FGA23
TH019.3
TPOX8,10
vWA18

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Cross-references
Cell line collections (Providers) NCI-PDMR; 12573
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1