ID   589616-265-R-J2-PDC
AC   CVCL_F4DD
DR   NCI-PDMR; 12573
CC   Part of: NCI Patient-Derived Model Repository.
CC   Population: Caucasian; Utah residents with ancestry from Northern and Western Europe.
CC   Characteristics: tumorigenic in NOD/SCID/IL2RgammaNULL (NSG) mice.
CC   Characteristics: Established from a patient-derived xenograft (PDX) in NOD/SCID/IL2RgammaNULL (NSG) mice.
CC   Doubling time: 53 hours (NCI-PDMR=12573).
CC   HLA typing: A*02:01,30:01; B*13:02,18:01; C*06:02,07:01 (NCI-PDMR=12573).
CC   Microsatellite instability: Stable (MSS) (NCI-PDMR=12573).
CC   Sequence variation: Mutation; HGNC; HGNC:3188; EED; Simple; p.X287_splice (c.861-1G>T); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 1 (NCI-PDMR=12573).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.P153Afs*28 (c.456dup); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 1 (NCI-PDMR=12573).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: In situ; Left thigh; UBERON=UBERON_0000376.
ST   Source(s): NCI-PDMR=12573
ST   Amelogenin: X,Y
ST   CSF1PO: 11,13
ST   D13S317: 8
ST   D16S539: 9,13
ST   D18S51: 15
ST   D19S433: 13,14
ST   D21S11: 27,31
ST   D2S1338: 18,22
ST   D3S1358: 17
ST   D5S818: 12,13
ST   D7S820: 10
ST   D8S1179: 10
ST   FGA: 23
ST   TH01: 9.3
ST   TPOX: 8,10
ST   vWA: 18
DI   NCIt; C3798; Malignant Peripheral Nerve Sheath Tumor
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   58Y
CA   Cancer cell line
DT   Created: 25-06-26; Last updated: 25-06-26; Version: 1
//