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Cellosaurus 485368-065-R3-J5-PDC (CVCL_F4DC)

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Cell line name 485368-065-R3-J5-PDC
Accession CVCL_F4DC
Resource Identification Initiative To cite this cell line use: 485368-065-R3-J5-PDC (RRID:CVCL_F4DC)
Comments Part of: NCI Patient-Derived Model Repository.
Population: Caucasian; Utah residents with ancestry from Northern and Western Europe.
Characteristics: tumorigenic in NOD/SCID/IL2RgammaNULL (NSG) mice.
Characteristics: Established from a patient-derived xenograft (PDX) in NOD/SCID/IL2RgammaNULL (NSG) mice.
Doubling time: 37 hours (NCI-PDMR=9767).
Microsatellite instability: Stable (MSS) (NCI-PDMR=9767).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:11110; ARID1A; Simple; p.E1387Rfs*94 (c.4159del); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 1 (NCI-PDMR=9767).
  • Mutation; HGNC; HGNC:14078; BACH2; Simple; p.R651* (c.1951C>T); Zygosity=Heterozygous; Note=Likely Oncogenic, variant allele frequency: 0.3665 (NCI-PDMR=9767).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.G12V (c.35G>T); Zygosity=Homozygous; Note=Oncogenic, variant allele frequency: 0.9058 (NCI-PDMR=9767).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.E298* (c.892G>T); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 0.9838 (NCI-PDMR=9767).
HLA typing Source: NCI-PDMR=9767
Class I
HLA-AA*02:01,23:01
HLA-BB*18:01,44:03
HLA-CC*04:01,07:01
Disease Pancreatic Adenocarcinoma (NCIt: C8294)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 43Y
Category Cancer cell line
STR profile Source(s): NCI-PDMR=9767

Markers:
AmelogeninX
CSF1PO10,11
D2S133819,20
D3S135817
D5S81811,12
D7S82012
D8S117914,15
D13S31711,13
D16S5399,11
D18S5113
D19S43312,14
D21S1129
FGA18,25
TH019.3
TPOX8,9
vWA18,19

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Cross-references
Cell line collections (Providers) NCI-PDMR; 9767
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1