ID   485368-065-R3-J5-PDC
AC   CVCL_F4DC
DR   NCI-PDMR; 9767
CC   Part of: NCI Patient-Derived Model Repository.
CC   Population: Caucasian; Utah residents with ancestry from Northern and Western Europe.
CC   Characteristics: tumorigenic in NOD/SCID/IL2RgammaNULL (NSG) mice.
CC   Characteristics: Established from a patient-derived xenograft (PDX) in NOD/SCID/IL2RgammaNULL (NSG) mice.
CC   Doubling time: 37 hours (NCI-PDMR=9767).
CC   HLA typing: A*02:01,23:01; B*18:01,44:03; C*04:01,07:01 (NCI-PDMR=9767).
CC   Microsatellite instability: Stable (MSS) (NCI-PDMR=9767).
CC   Sequence variation: Mutation; HGNC; HGNC:11110; ARID1A; Simple; p.E1387Rfs*94 (c.4159del); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 1 (NCI-PDMR=9767).
CC   Sequence variation: Mutation; HGNC; HGNC:14078; BACH2; Simple; p.R651* (c.1951C>T); Zygosity=Heterozygous; Note=Likely Oncogenic, variant allele frequency: 0.3665 (NCI-PDMR=9767).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.G12V (c.35G>T); Zygosity=Homozygous; Note=Oncogenic, variant allele frequency: 0.9058 (NCI-PDMR=9767).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.E298* (c.892G>T); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 0.9838 (NCI-PDMR=9767).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
ST   Source(s): NCI-PDMR=9767
ST   Amelogenin: X
ST   CSF1PO: 10,11
ST   D13S317: 11,13
ST   D16S539: 9,11
ST   D18S51: 13
ST   D19S433: 12,14
ST   D21S11: 29
ST   D2S1338: 19,20
ST   D3S1358: 17
ST   D5S818: 11,12
ST   D7S820: 12
ST   D8S1179: 14,15
ST   FGA: 18,25
ST   TH01: 9.3
ST   TPOX: 8,9
ST   vWA: 18,19
DI   NCIt; C8294; Pancreatic Adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   43Y
CA   Cancer cell line
DT   Created: 25-06-26; Last updated: 25-06-26; Version: 1
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