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Cellosaurus 349418-098-R-PDC (CVCL_F4DA)

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Cell line name 349418-098-R-PDC
Accession CVCL_F4DA
Resource Identification Initiative To cite this cell line use: 349418-098-R-PDC (RRID:CVCL_F4DA)
Comments Part of: NCI Patient-Derived Model Repository.
Population: Caucasian; Utah residents with ancestry from Northern and Western Europe.
Characteristics: tumorigenic in NOD/SCID/IL2RgammaNULL (NSG) mice.
Doubling time: 25.5 hours (NCI-PDMR=1097).
Microsatellite instability: Stable (MSS) (NCI-PDMR=1097).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Lung, left lower lobe; UBERON=UBERON_0008953.
Sequence variations
  • Mutation; HGNC; HGNC:11110; ARID1A; Simple; p.S2249* (c.6746C>G); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 1 (NCI-PDMR=1097).
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.V600E (c.1799T>A); Zygosity=Heterozygous; Note=Oncogenic, variant allele frequency: 0.4894 (NCI-PDMR=1097).
  • Mutation; HGNC; HGNC:3444; ERF; Simple; p.Q263* (c.787C>T); Zygosity=Heterozygous; Note=Likely Oncogenic, variant allele frequency: 0.48 (NCI-PDMR=1097).
  • Mutation; HGNC; HGNC:4550; GPS2; Simple; p.X160_splice (c.480+1dup); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 1 (NCI-PDMR=1097).
HLA typing Source: NCI-PDMR=1097
Class I
HLA-AA*01:01,11:01
HLA-BB*08:01,44:02
HLA-CC*05:01,07:01
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 71Y
Category Cancer cell line
STR profile Source(s): NCI-PDMR=1097

Markers:
AmelogeninX,Y
CSF1PO11,12
D2S133817,18
D3S135815,17
D5S81811,12
D7S8208,9
D8S117914,15
D13S3178,9
D16S53910,13
D18S5112,14
D19S43313,14
D21S1128,30
FGA20,24
TH016,9.3
TPOX8,11
vWA17,20

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Cross-references
Cell line collections (Providers) NCI-PDMR; 1097
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1