ID   349418-098-R-PDC
AC   CVCL_F4DA
DR   NCI-PDMR; 1097
CC   Part of: NCI Patient-Derived Model Repository.
CC   Population: Caucasian; Utah residents with ancestry from Northern and Western Europe.
CC   Characteristics: tumorigenic in NOD/SCID/IL2RgammaNULL (NSG) mice.
CC   Doubling time: 25.5 hours (NCI-PDMR=1097).
CC   HLA typing: A*01:01,11:01; B*08:01,44:02; C*05:01,07:01 (NCI-PDMR=1097).
CC   Microsatellite instability: Stable (MSS) (NCI-PDMR=1097).
CC   Sequence variation: Mutation; HGNC; HGNC:11110; ARID1A; Simple; p.S2249* (c.6746C>G); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 1 (NCI-PDMR=1097).
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.V600E (c.1799T>A); Zygosity=Heterozygous; Note=Oncogenic, variant allele frequency: 0.4894 (NCI-PDMR=1097).
CC   Sequence variation: Mutation; HGNC; HGNC:3444; ERF; Simple; p.Q263* (c.787C>T); Zygosity=Heterozygous; Note=Likely Oncogenic, variant allele frequency: 0.48 (NCI-PDMR=1097).
CC   Sequence variation: Mutation; HGNC; HGNC:4550; GPS2; Simple; p.X160_splice (c.480+1dup); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 1 (NCI-PDMR=1097).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: In situ; Lung, left lower lobe; UBERON=UBERON_0008953.
ST   Source(s): NCI-PDMR=1097
ST   Amelogenin: X,Y
ST   CSF1PO: 11,12
ST   D13S317: 8,9
ST   D16S539: 10,13
ST   D18S51: 12,14
ST   D19S433: 13,14
ST   D21S11: 28,30
ST   D2S1338: 17,18
ST   D3S1358: 15,17
ST   D5S818: 11,12
ST   D7S820: 8,9
ST   D8S1179: 14,15
ST   FGA: 20,24
ST   TH01: 6,9.3
ST   TPOX: 8,11
ST   vWA: 17,20
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   71Y
CA   Cancer cell line
DT   Created: 25-06-26; Last updated: 25-06-26; Version: 1
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