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Cellosaurus 242566-281-R-J2-PDC (CVCL_F4D7)

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Cell line name 242566-281-R-J2-PDC
Accession CVCL_F4D7
Resource Identification Initiative To cite this cell line use: 242566-281-R-J2-PDC (RRID:CVCL_F4D7)
Comments Part of: NCI Patient-Derived Model Repository.
Population: Caucasian; Utah residents with ancestry from Northern and Western Europe.
Characteristics: tumorigenic in NOD/SCID/IL2RgammaNULL (NSG) mice.
Characteristics: Established from a patient-derived xenograft (PDX) in NOD/SCID/IL2RgammaNULL (NSG) mice.
Doubling time: 58 hours (NCI-PDMR=8367).
Microsatellite instability: Stable (MSS) (NCI-PDMR=8367).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
  • Mutation; HGNC; HGNC:11110; ARID1A; Simple; p.R1722* (c.5164C>T); Zygosity=Heterozygous; Note=Likely Oncogenic, variant allele frequency: 0.4848 (NCI-PDMR=8367).
  • Mutation; HGNC; HGNC:4390; GNAQ; Simple; p.T96S (c.286A>T); Zygosity=Unspecified; Note=Likely Oncogenic, variant allele frequency: 0.1923 (NCI-PDMR=8367).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.G12D (c.35G>A); Zygosity=Heterozygous; Note=Oncogenic, variant allele frequency: 0.4791 (NCI-PDMR=8367).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.R213* (c.637C>T); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 0.9936 (NCI-PDMR=8367).
HLA typing Source: NCI-PDMR=8367
Class I
HLA-AA*03:01,32:01
HLA-BB*07:02,57:01
HLA-CC*06:02,07:02
Disease Pancreatic Adenocarcinoma (NCIt: C8294)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 57Y
Category Cancer cell line
STR profile Source(s): NCI-PDMR=8367

Markers:
AmelogeninX
CSF1PO10,13
D2S133819,23
D3S135814,16
D5S81811
D7S8209,12
D8S117911,13
D13S31711,12
D16S53912,13
D18S5116
D19S43312,14
D21S1130
FGA19
TH016,7
TPOX8
vWA16,18

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Cross-references
Cell line collections (Providers) NCI-PDMR; 8367
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1