ID   242566-281-R-J2-PDC
AC   CVCL_F4D7
DR   NCI-PDMR; 8367
CC   Part of: NCI Patient-Derived Model Repository.
CC   Population: Caucasian; Utah residents with ancestry from Northern and Western Europe.
CC   Characteristics: tumorigenic in NOD/SCID/IL2RgammaNULL (NSG) mice.
CC   Characteristics: Established from a patient-derived xenograft (PDX) in NOD/SCID/IL2RgammaNULL (NSG) mice.
CC   Doubling time: 58 hours (NCI-PDMR=8367).
CC   HLA typing: A*03:01,32:01; B*07:02,57:01; C*06:02,07:02 (NCI-PDMR=8367).
CC   Microsatellite instability: Stable (MSS) (NCI-PDMR=8367).
CC   Sequence variation: Mutation; HGNC; HGNC:11110; ARID1A; Simple; p.R1722* (c.5164C>T); Zygosity=Heterozygous; Note=Likely Oncogenic, variant allele frequency: 0.4848 (NCI-PDMR=8367).
CC   Sequence variation: Mutation; HGNC; HGNC:4390; GNAQ; Simple; p.T96S (c.286A>T); Zygosity=Unspecified; Note=Likely Oncogenic, variant allele frequency: 0.1923 (NCI-PDMR=8367).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.G12D (c.35G>A); Zygosity=Heterozygous; Note=Oncogenic, variant allele frequency: 0.4791 (NCI-PDMR=8367).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.R213* (c.637C>T); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 0.9936 (NCI-PDMR=8367).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
ST   Source(s): NCI-PDMR=8367
ST   Amelogenin: X
ST   CSF1PO: 10,13
ST   D13S317: 11,12
ST   D16S539: 12,13
ST   D18S51: 16
ST   D19S433: 12,14
ST   D21S11: 30
ST   D2S1338: 19,23
ST   D3S1358: 14,16
ST   D5S818: 11
ST   D7S820: 9,12
ST   D8S1179: 11,13
ST   FGA: 19
ST   TH01: 6,7
ST   TPOX: 8
ST   vWA: 16,18
DI   NCIt; C8294; Pancreatic Adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   57Y
CA   Cancer cell line
DT   Created: 25-06-26; Last updated: 25-06-26; Version: 1
//