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Cellosaurus 176247-063-R-J2-PDC (CVCL_F4D6)

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Cell line name 176247-063-R-J2-PDC
Accession CVCL_F4D6
Resource Identification Initiative To cite this cell line use: 176247-063-R-J2-PDC (RRID:CVCL_F4D6)
Comments Part of: NCI Patient-Derived Model Repository.
Population: Caucasian; Utah residents with ancestry from Northern and Western Europe.
Characteristics: tumorigenic in NOD/SCID/IL2RgammaNULL (NSG) mice.
Characteristics: Established from a 3D organoid culture of a patient-derived xenograft (PDX) in NOD/SCID/IL2RgammaNULL (NSG) mice.
Doubling time: 65 hours (NCI-PDMR=11225).
Microsatellite instability: Stable (MSS) (NCI-PDMR=11225).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.T1368Kfs*4 (c.4103_4110del); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 1 (NCI-PDMR=11225).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.R175H (c.524G>A); Zygosity=Homozygous; Note=Oncogenic, variant allele frequency: 1 (NCI-PDMR=11225).
HLA typing Source: NCI-PDMR=11225
Class I
HLA-AA*02:01,03:01
HLA-BB*08:01,14:03
HLA-CC*07:01,08:02
Disease Colon Adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 52Y
Category Cancer cell line
STR profile Source(s): NCI-PDMR=11225

Markers:
AmelogeninX
CSF1PO10
D2S133819,24
D3S135815
D5S81811
D7S8209,12
D8S11798,14
D13S31712
D16S53911,13
D18S5114
D19S43312,13
D21S1128,31.2
FGA20,21
TH016,7
TPOX8,10,11
vWA17

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Cross-references
Cell line collections (Providers) NCI-PDMR; 11225
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1