ID   176247-063-R-J2-PDC
AC   CVCL_F4D6
DR   NCI-PDMR; 11225
CC   Part of: NCI Patient-Derived Model Repository.
CC   Population: Caucasian; Utah residents with ancestry from Northern and Western Europe.
CC   Characteristics: tumorigenic in NOD/SCID/IL2RgammaNULL (NSG) mice.
CC   Characteristics: Established from a 3D organoid culture of a patient-derived xenograft (PDX) in NOD/SCID/IL2RgammaNULL (NSG) mice.
CC   Doubling time: 65 hours (NCI-PDMR=11225).
CC   HLA typing: A*02:01,03:01; B*08:01,14:03; C*07:01,08:02 (NCI-PDMR=11225).
CC   Microsatellite instability: Stable (MSS) (NCI-PDMR=11225).
CC   Sequence variation: Mutation; HGNC; HGNC:583; APC; Simple; p.T1368Kfs*4 (c.4103_4110del); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 1 (NCI-PDMR=11225).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.R175H (c.524G>A); Zygosity=Homozygous; Note=Oncogenic, variant allele frequency: 1 (NCI-PDMR=11225).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: In situ; Colon; UBERON=UBERON_0001155.
ST   Source(s): NCI-PDMR=11225
ST   Amelogenin: X
ST   CSF1PO: 10
ST   D13S317: 12
ST   D16S539: 11,13
ST   D18S51: 14
ST   D19S433: 12,13
ST   D21S11: 28,31.2
ST   D2S1338: 19,24
ST   D3S1358: 15
ST   D5S818: 11
ST   D7S820: 9,12
ST   D8S1179: 8,14
ST   FGA: 20,21
ST   TH01: 6,7
ST   TPOX: 8,10,11
ST   vWA: 17
DI   NCIt; C4349; Colon Adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   52Y
CA   Cancer cell line
DT   Created: 25-06-26; Last updated: 25-06-26; Version: 1
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