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Cellosaurus 114551-080-T-J1-PDC (CVCL_F4D5)

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Cell line name 114551-080-T-J1-PDC
Accession CVCL_F4D5
Resource Identification Initiative To cite this cell line use: 114551-080-T-J1-PDC (RRID:CVCL_F4D5)
Comments Part of: NCI Patient-Derived Model Repository.
Population: African; Yoruba in Ibadan, Nigeria (YRI).
Characteristics: tumorigenic in NOD/SCID/IL2RgammaNULL (NSG) mice.
Characteristics: Established from a patient-derived xenograft (PDX) in NOD/SCID/IL2RgammaNULL (NSG) mice.
Doubling time: 27 hours (NCI-PDMR=12781).
Microsatellite instability: Stable (MSS) (NCI-PDMR=12781).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
Derived from site: Metastatic; Lung, pleura; UBERON=UBERON_0000977.
Sequence variations
  • Mutation; HGNC; HGNC:20893; BCOR; Simple; p.R1231Gfs*7 (c.3691del); Zygosity=Heterozygous; Note=Likely Oncogenic, variant allele frequency: 0.4118 (NCI-PDMR=12781).
  • Mutation; HGNC; HGNC:18185; ERRFI1; Simple; MUTATED (c.-73-1G>A); Zygosity=Heterozygous; Note=Likely Oncogenic, variant allele frequency: 0.4737 (NCI-PDMR=12781).
  • Mutation; HGNC; HGNC:16712; FBXW7; Simple; p.R222* (c.664C>T); Zygosity=Heterozygous; Note=Likely Oncogenic, variant allele frequency: 0.5321 (NCI-PDMR=12781).
  • Mutation; HGNC; HGNC:16712; FBXW7; Simple; p.R479Q (c.1436G>A); Zygosity=Heterozygous; Note=Oncogenic, variant allele frequency: 0.4397 (NCI-PDMR=12781).
  • Mutation; HGNC; HGNC:6515; LATS2; Simple; p.P473_A480dup (c.1416_1439dup); Zygosity=Heterozygous; Note=Likely Oncogenic, variant allele frequency: 0.4242 (NCI-PDMR=12781).
  • Mutation; HGNC; HGNC:10249; ROBO1; Simple; p.R922H (c.2765G>A); Zygosity=Heterozygous; Note=Likely Oncogenic, variant allele frequency: 0.4679 (NCI-PDMR=12781).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.R175H (c.524G>A); Zygosity=Homozygous; Note=Oncogenic, variant allele frequency: 1 (NCI-PDMR=12781).
  • Mutation; HGNC; HGNC:13054; ZMYM3; Simple; p.L85Afs*4 (c.252dup); Zygosity=Heterozygous; Note=Likely Oncogenic, variant allele frequency: 0.4389 (NCI-PDMR=12781).
HLA typing Source: NCI-PDMR=12781
Class I
HLA-AA*03:01,30:01
HLA-BB*42:01,49:01
HLA-CC*07:01,17:01
Disease Malignant Salivary Gland Neoplasm (NCIt: C3811)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 52Y
Category Cancer cell line
STR profile Source(s): NCI-PDMR=12781

Markers:
AmelogeninX
CSF1PO10,11
D2S133815,21
D3S135815,18
D5S81812,13
D7S82010,12
D8S117912,14
D13S3178,11
D16S53912
D18S5117,21
D19S43313,13.2
D21S1129
FGA23,24
TH018
TPOX9,11
vWA17

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Cross-references
Cell line collections (Providers) NCI-PDMR; 12781
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1