ID   114551-080-T-J1-PDC
AC   CVCL_F4D5
DR   NCI-PDMR; 12781
CC   Part of: NCI Patient-Derived Model Repository.
CC   Population: African; Yoruba in Ibadan, Nigeria (YRI).
CC   Characteristics: tumorigenic in NOD/SCID/IL2RgammaNULL (NSG) mice.
CC   Characteristics: Established from a patient-derived xenograft (PDX) in NOD/SCID/IL2RgammaNULL (NSG) mice.
CC   Doubling time: 27 hours (NCI-PDMR=12781).
CC   HLA typing: A*03:01,30:01; B*42:01,49:01; C*07:01,17:01 (NCI-PDMR=12781).
CC   Microsatellite instability: Stable (MSS) (NCI-PDMR=12781).
CC   Sequence variation: Mutation; HGNC; HGNC:20893; BCOR; Simple; p.R1231Gfs*7 (c.3691del); Zygosity=Heterozygous; Note=Likely Oncogenic, variant allele frequency: 0.4118 (NCI-PDMR=12781).
CC   Sequence variation: Mutation; HGNC; HGNC:18185; ERRFI1; Simple; MUTATED (c.-73-1G>A); Zygosity=Heterozygous; Note=Likely Oncogenic, variant allele frequency: 0.4737 (NCI-PDMR=12781).
CC   Sequence variation: Mutation; HGNC; HGNC:16712; FBXW7; Simple; p.R222* (c.664C>T); Zygosity=Heterozygous; Note=Likely Oncogenic, variant allele frequency: 0.5321 (NCI-PDMR=12781).
CC   Sequence variation: Mutation; HGNC; HGNC:16712; FBXW7; Simple; p.R479Q (c.1436G>A); Zygosity=Heterozygous; Note=Oncogenic, variant allele frequency: 0.4397 (NCI-PDMR=12781).
CC   Sequence variation: Mutation; HGNC; HGNC:6515; LATS2; Simple; p.P473_A480dup (c.1416_1439dup); Zygosity=Heterozygous; Note=Likely Oncogenic, variant allele frequency: 0.4242 (NCI-PDMR=12781).
CC   Sequence variation: Mutation; HGNC; HGNC:10249; ROBO1; Simple; p.R922H (c.2765G>A); Zygosity=Heterozygous; Note=Likely Oncogenic, variant allele frequency: 0.4679 (NCI-PDMR=12781).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.R175H (c.524G>A); Zygosity=Homozygous; Note=Oncogenic, variant allele frequency: 1 (NCI-PDMR=12781).
CC   Sequence variation: Mutation; HGNC; HGNC:13054; ZMYM3; Simple; p.L85Afs*4 (c.252dup); Zygosity=Heterozygous; Note=Likely Oncogenic, variant allele frequency: 0.4389 (NCI-PDMR=12781).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: Metastatic; Lung, pleura; UBERON=UBERON_0000977.
ST   Source(s): NCI-PDMR=12781
ST   Amelogenin: X
ST   CSF1PO: 10,11
ST   D13S317: 8,11
ST   D16S539: 12
ST   D18S51: 17,21
ST   D19S433: 13,13.2
ST   D21S11: 29
ST   D2S1338: 15,21
ST   D3S1358: 15,18
ST   D5S818: 12,13
ST   D7S820: 10,12
ST   D8S1179: 12,14
ST   FGA: 23,24
ST   TH01: 8
ST   TPOX: 9,11
ST   vWA: 17
DI   NCIt; C3811; Malignant Salivary Gland Neoplasm
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   52Y
CA   Cancer cell line
DT   Created: 25-06-26; Last updated: 25-06-26; Version: 1
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