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Cellosaurus Human TP53 Knockout Cell Line - MV4-11 (CVCL_F4CE)

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Cell line name Human TP53 Knockout Cell Line - MV4-11
Accession CVCL_F4CE
Resource Identification Initiative To cite this cell line use: Human TP53 Knockout Cell Line - MV4-11 (RRID:CVCL_F4CE)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:11998; TP53.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; HGNC:7135; AFF1 + HGNC; HGNC:7132; KMT2A; Name(s)=KMT2A-AFF1, MLL-AFF1, ALL-1/AF4 (from parent cell line).
  • Mutation; HGNC; HGNC:3765; FLT3; Unexplicit; Internal tandem duplication (FLT3-ITD); ClinVar=VCV000016270; Zygosity=Unspecified (from parent cell line).
Disease Childhood acute monocytic leukemia (NCIt: C9163)
Acute monoblastic/monocytic leukemia (ORDO: Orphanet_514)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0064 (MV4-11)
Sex of cell Male
Age at sampling 10Y
Category Cancer cell line
Web pages Provider; Creative Biogene; CSC-RT2704; https://www.creative-biogene.com/human-tp53-knockout-cell-line-mv-4-11-item-csc-rt2704-444908.html
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1