Cellosaurus EPC2-hTERT (CVCL_F4C2)
| Cell line name | EPC2-hTERT |
|---|---|
| Accession | CVCL_F4C2 |
| Resource Identification Initiative | To cite this cell line use: EPC2-hTERT (RRID:CVCL_F4C2) |
| Comments | Characteristics: p16INK4a (CDKN2A) is wild-type and functionally active (UV-inducible; binds CDK4/6). p53 (TP53) is wild-type and functionally active (PubMed=12939398). Characteristics: Expresses cytokeratins 5 and 14 (PubMed=12939398). Characteristics: Displays basal cell hyperplasia but not malignant transformation in organotypic culture (PubMed=12939398). Karyotypic information: Normal diploid karyotype (PubMed=12939398). Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT. Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Derived from site: In situ; Epithelium of esophagus; UBERON=UBERON_0001976. Cell type: Keratinocyte; CL=CL_0000312. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_F4C3 (EPC2) |
| Sex of cell | Sex unspecified |
| Age at sampling | Age unspecified |
| Category | Telomerase immortalized cell line |
| Publications | PubMed=12939398 |
| Entry history | |
| Entry creation | 25-Jun-2026 |
| Last entry update | 25-Jun-2026 |
| Version number | 1 |