Cellosaurus TRIP13 (AID) DLD-1 T-Rex Flp-In H2BmRFP+TIR1-9Myc+ (CVCL_F4BX)
| Cell line name | TRIP13 (AID) DLD-1 T-Rex Flp-In H2BmRFP+TIR1-9Myc+ |
|---|---|
| Synonyms | DLD-1 TRIP13 (AID); TRIP13AID |
| Accession | CVCL_F4BX |
| Resource Identification Initiative | To cite this cell line use: TRIP13 (AID) DLD-1 T-Rex Flp-In H2BmRFP+TIR1-9Myc+ (RRID:CVCL_F4BX) |
| Comments | Population: Caucasian. Characteristics: Contains an inducible system enabling rapid depletion of TRIP13 via auxin-inducible degron (AID) tagging of both endogenous TRIP13 alleles. Genetic integration: Method=CRISPR/Cas9; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP). Genetic integration: Method=CRISPR/Cas9; Gene=HGNC; HGNC:12307; TRIP13 (Note=With N-ter AID and GFP tags). Genetic integration: Method=CRISPR/Cas9; Gene=UniProtKB; P93830; Arabidopsis thaliana IAA17 (Note=Acts as an auxin-inducible degron (AID)). Genetic integration: Method=Transduction; Gene=UniProtKB; Q7XVM8; Oryza sativa subsp. japonica TIR1-like protein Os04g0395600 (Note=With a 9xMyc tag). Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Genetic integration: Method=Transfection; Gene=UniProtKB; P00722; Escherichia coli beta-galactosidase (lacZ). Genetic integration: Method=Transfection; Gene=UniProtKB; P04483; Escherichia coli Tn10 tetR. Genetic integration: Method=Transfection; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR). Genetic integration: Method=Transfection/transduction; Gene=FPbase; 5YCFA; mRFP1 (Note=Bright red fluorescent protein derived from drFP583 (DsRed)). Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:4761; H2BC11. Derived from site: In situ; Colon; UBERON=UBERON_0001155. Cell type: Epithelial cell of colon; CL=CL_0011108. |
| Disease | Colon adenocarcinoma (NCIt: C4349) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_F4BY (DLD-1 T-REX Flp-ln H2BmRFP TIR1-9MyC) |
| Sex of cell | Male |
| Age at sampling | 67Y |
| Category | Cancer cell line |
| Publications | PubMed=30341343; DOI=10.1038/s41467-018-06774-1; PMCID=PMC6195577 |
| Entry history | |
| Entry creation | 25-Jun-2026 |
| Last entry update | 25-Jun-2026 |
| Version number | 1 |