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Cellosaurus EB [Human colon carcinoma] (CVCL_F287)

[Text version]
Cell line name EB [Human colon carcinoma]
Synonyms HCT-EB; HCT EB
Accession CVCL_F287
Resource Identification Initiative To cite this cell line use: EB [Human colon carcinoma] (RRID:CVCL_F287)
Comments Microsatellite instability: Stable (MSS) (PubMed=9000147; PubMed=24042735; PubMed=28683746).
Omics: Proteomics; Expression; Reverse-phase protein array.
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Miscellaneous: STR profile mentioned but not shown in PubMed=24042735; obtained from personal communication of Lind, Guro Elisabeth.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
Disease Colon carcinoma (NCIt: C4910)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=24042735

Markers:
AmelogeninX
CSF1PO12,15
D2S133819
D3S135814,15
D5S81810,11
D7S8208,9
D8S117911,13
D13S31711
D16S53911,12
D18S5114,16
D19S43313
D21S1128,32.2
FGA21,22.2
TH019,9.3
TPOX8,11
vWA15,16

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Publications

PubMed=7329817
Michael G. Brattain, Diane E. Brattain, W. David Fine, F. Mahnaz Khaled, Michael E. Marks, Pamela M. Kimball, Laurie A. Arcolano, Bernice H. Danbury;
Initiation and characterization of cultures of human colonic carcinoma with different biological characteristics utilizing feeder layers of confluent fibroblasts.
Oncodev. Biol. Med. 2:355-366(1981)

PubMed=6437669; DOI=10.1007/BF00048384
Michael G. Brattain, Alan E. Levine, Subhas Chakrabarty, Lynn C. Yeoman, James K.V. Willson, Bing Long;
Heterogeneity of human colon carcinoma.
Cancer Metastasis Rev. 3:177-191(1984)

PubMed=3349466
Isabelle Chantret, Alain Barbat, Elisabeth Dussaulx, Michael G. Brattain, Alain Zweibaum;
Epithelial polarity, villin expression, and enterocytic differentiation of cultured human colon carcinoma cells: a survey of twenty cell lines.
Cancer Res. 48:1936-1942(1988)

PubMed=9000147
Paul-Henri Cottu, Francoise Muzeau, Anne Estreicher, Jean-Francois Flejou, Richard D. Iggo, Gilles Thomas, Richard Hamelin;
Inverse correlation between RER+ status and p53 mutation in colorectal cancer cell lines.
Oncogene 13:2727-2730(1996)

PubMed=9000572
Jean-Marc Hoang, Paul-Henri Cottu, Benedicte Thuille, Remi J. Salmon, Gilles Thomas, Richard Hamelin;
BAT-26, an indicator of the replication error phenotype in colorectal cancers and cell lines.
Cancer Res. 57:300-303(1997)

PubMed=11526487; DOI=10.1038/sj.onc.1204611
Jacqueline Gayet, Xiao-Ping Zhou, Alex Duval, Sandra Rolland, Jean-Marc Hoang, Paul-Henri Cottu, Richard Hamelin;
Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines.
Oncogene 20:5025-5032(2001)

PubMed=24042735; DOI=10.1038/oncsis.2013.35; PMCID=PMC3816225
Deeqa Ahmed, Peter W. Eide, Ina A. Eilertsen, Stine A. Danielsen, Mette Eknaes, Merete Hektoen, Guro Elisabeth Lind, Ragnhild Adelheid Lothe;
Epigenetic and genetic features of 24 colon cancer cell lines.
Oncogenesis 2:e71.1-e71.8(2013)

PubMed=28683746; DOI=10.1186/s12943-017-0691-y; PMCID=PMC5498998
Kaja Christine Graue Berg, Peter W. Eide, Ina A. Eilertsen, Bjarne Johannessen, Jarle Bruun, Stine A. Danielsen, Merete Bjornslett, Leonardo Andres Meza-Zepeda, Mette Eknaes, Guro Elisabeth Lind, Ola Myklebost ...Show all 14 authors... , Rolf Inge Skotheim, Anita Sveen, Ragnhild Adelheid Lothe; Show fewer authors
Multi-omics of 34 colorectal cancer cell lines -- a resource for biomedical studies.
Mol. Cancer 16:116.1-116.16(2017)

Cross-references
Cell line databases/resources cancercelllines; CVCL_F287
ColonAtlas; EB
Encyclopedic resources Wikidata; Q54831736
Gene expression databases GEO; GSM2549998
Polymorphism and mutation databases Cosmic; 711274
Cosmic; 887228
Cosmic; 889530
Cosmic; 948124
Cosmic; 1057762
Entry history
Entry creation22-Oct-2012
Last entry update14-Aug-2025
Version number18