Cellosaurus logo
expasy logo

Cellosaurus EB [Human colon carcinoma] (CVCL_F287)

[Text version]
Cell line name EB [Human colon carcinoma]
Synonyms HCT-EB; HCT EB
Accession CVCL_F287
Resource Identification Initiative To cite this cell line use: EB [Human colon carcinoma] (RRID:CVCL_F287)
Comments Microsatellite instability: Stable (MSS) (PubMed=9000147; PubMed=24042735; PubMed=28683746).
Omics: Protein expression by reverse-phase protein arrays.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Miscellaneous: STR profile mentioned but not shown in PubMed=24042735; obtained by personal communication of Lind G.E.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
Disease Colon carcinoma (NCIt: C4910)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=24042735

Markers:
AmelogeninX
CSF1PO12,15
D2S133819
D3S135814,15
D5S81810,11
D7S8208,9
D8S117911,13
D13S31711
D16S53911,12
D18S5114,16
D19S43313
D21S1128,32.2
FGA21,22.2
TH019,9.3
TPOX8,11
vWA15,16

Run an STR similarity search on this cell line
Publications

PubMed=7329817
Brattain M.G., Brattain D.E., Fine W.D., Khaled F.M., Marks M.E., Kimball P.M., Arcolano L.A., Danbury B.H.
Initiation and characterization of cultures of human colonic carcinoma with different biological characteristics utilizing feeder layers of confluent fibroblasts.
Oncodev. Biol. Med. 2:355-366(1981)

PubMed=6437669; DOI=10.1007/BF00048384
Brattain M.G., Levine A.E., Chakrabarty S., Yeoman L.C., Willson J.K.V., Long B.
Heterogeneity of human colon carcinoma.
Cancer Metastasis Rev. 3:177-191(1984)

PubMed=3349466
Chantret I., Barbat A., Dussaulx E., Brattain M.G., Zweibaum A.
Epithelial polarity, villin expression, and enterocytic differentiation of cultured human colon carcinoma cells: a survey of twenty cell lines.
Cancer Res. 48:1936-1942(1988)

PubMed=9000147
Cottu P.H., Muzeau F., Estreicher A., Flejou J.-F., Iggo R.D., Thomas G., Hamelin R.
Inverse correlation between RER+ status and p53 mutation in colorectal cancer cell lines.
Oncogene 13:2727-2730(1996)

PubMed=9000572
Hoang J.-M., Cottu P.H., Thuille B., Salmon R.J., Thomas G., Hamelin R.
BAT-26, an indicator of the replication error phenotype in colorectal cancers and cell lines.
Cancer Res. 57:300-303(1997)

PubMed=11526487; DOI=10.1038/sj.onc.1204611
Gayet J., Zhou X.-P., Duval A., Rolland S., Hoang J.-M., Cottu P.H., Hamelin R.
Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines.
Oncogene 20:5025-5032(2001)

PubMed=24042735; DOI=10.1038/oncsis.2013.35
Ahmed D., Eide P.W., Eilertsen I.A., Danielsen S.A., Eknaes M., Hektoen M., Lind G.E., Lothe R.A.
Epigenetic and genetic features of 24 colon cancer cell lines.
Oncogenesis 2:e71.1-e71.8(2013)

PubMed=28683746; DOI=10.1186/s12943-017-0691-y
Berg K.C.G., Eide P.W., Eilertsen I.A., Johannessen B., Bruun J., Danielsen S.A., Bjornslett M., Meza-Zepeda L.A., Eknaes M., Lind G.E., Myklebost O., Skotheim R.I., Sveen A., Lothe R.A.
Multi-omics of 34 colorectal cancer cell lines -- a resource for biomedical studies.
Mol. Cancer 16:116.1-116.16(2017)

Cross-references
Cell line databases/resources cancercelllines; CVCL_F287
ColonAtlas; EB
Encyclopedic resources Wikidata; Q54831736
Gene expression databases GEO; GSM2549998
Polymorphism and mutation databases Cosmic; 711274
Cosmic; 887228
Cosmic; 889530
Cosmic; 948124
Cosmic; 1057762
Entry history
Entry creation22-Oct-2012
Last entry update05-Oct-2023
Version number14