ID   EB [Human colon carcinoma]
AC   CVCL_F287
SY   HCT-EB; HCT EB
DR   cancercelllines; CVCL_F287
DR   ColonAtlas; EB
DR   Cosmic; 711274
DR   Cosmic; 887228
DR   Cosmic; 889530
DR   Cosmic; 948124
DR   Cosmic; 1057762
DR   GEO; GSM2549998
DR   Wikidata; Q54831736
RX   PubMed=3349466;
RX   PubMed=6437669;
RX   PubMed=7329817;
RX   PubMed=9000147;
RX   PubMed=9000572;
RX   PubMed=11526487;
RX   PubMed=24042735;
RX   PubMed=28683746;
CC   Microsatellite instability: Stable (MSS) (PubMed=9000147; PubMed=24042735; PubMed=28683746).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (PubMed=24042735; PubMed=28683746).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Unspecified (PubMed=24042735; PubMed=28683746).
CC   Omics: Proteomics; Expression; Reverse-phase protein array.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Variations; SNP array analysis.
CC   Miscellaneous: STR profile mentioned but not shown in PubMed=24042735; obtained from personal communication of Lind, Guro Elisabeth.
CC   Derived from site: In situ; Colon; UBERON=UBERON_0001155.
ST   Source(s): PubMed=24042735
ST   Amelogenin: X
ST   CSF1PO: 12,15
ST   D13S317: 11
ST   D16S539: 11,12
ST   D18S51: 14,16
ST   D19S433: 13
ST   D21S11: 28,32.2
ST   D2S1338: 19
ST   D3S1358: 14,15
ST   D5S818: 10,11
ST   D7S820: 8,9
ST   D8S1179: 11,13
ST   FGA: 21,22.2
ST   TH01: 9,9.3
ST   TPOX: 8,11
ST   vWA: 15,16
DI   NCIt; C4910; Colon carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 14-08-25; Version: 18
//
RX   PubMed=28683746; DOI=10.1186/s12943-017-0691-y; PMCID=PMC5498998;
RA   Berg, Kaja Christine Graue
RA   Eide, Peter W.
RA   Eilertsen, Ina A.
RA   Johannessen, Bjarne
RA   Bruun, Jarle
RA   Danielsen, Stine A.
RA   Bjornslett, Merete
RA   Meza-Zepeda, Leonardo Andres
RA   Eknaes, Mette
RA   Lind, Guro Elisabeth
RA   Myklebost, Ola
RA   Skotheim, Rolf Inge
RA   Sveen, Anita
RA   Lothe, Ragnhild Adelheid
RT   "Multi-omics of 34 colorectal cancer cell lines -- a resource for
RT   biomedical studies.";
RL   Mol. Cancer 16:116.1-116.16(2017).
//
RX   PubMed=9000147;
RA   Cottu, Paul-Henri
RA   Muzeau, Francoise
RA   Estreicher, Anne
RA   Flejou, Jean-Francois
RA   Iggo, Richard D.
RA   Thomas, Gilles
RA   Hamelin, Richard
RT   "Inverse correlation between RER+ status and p53 mutation in
RT   colorectal cancer cell lines.";
RL   Oncogene 13:2727-2730(1996).
//
RX   PubMed=9000572;
RA   Hoang, Jean-Marc
RA   Cottu, Paul-Henri
RA   Thuille, Benedicte
RA   Salmon, Remi J.
RA   Thomas, Gilles
RA   Hamelin, Richard
RT   "BAT-26, an indicator of the replication error phenotype in colorectal
RT   cancers and cell lines.";
RL   Cancer Res. 57:300-303(1997).
//
RX   PubMed=24042735; DOI=10.1038/oncsis.2013.35; PMCID=PMC3816225;
RA   Ahmed, Deeqa
RA   Eide, Peter W.
RA   Eilertsen, Ina A.
RA   Danielsen, Stine A.
RA   Eknaes, Mette
RA   Hektoen, Merete
RA   Lind, Guro Elisabeth
RA   Lothe, Ragnhild Adelheid
RT   "Epigenetic and genetic features of 24 colon cancer cell lines.";
RL   Oncogenesis 2:e71.1-e71.8(2013).
//
RX   PubMed=3349466;
RA   Chantret, Isabelle
RA   Barbat, Alain
RA   Dussaulx, Elisabeth
RA   Brattain, Michael G.
RA   Zweibaum, Alain
RT   "Epithelial polarity, villin expression, and enterocytic
RT   differentiation of cultured human colon carcinoma cells: a survey of
RT   twenty cell lines.";
RL   Cancer Res. 48:1936-1942(1988).
//
RX   PubMed=11526487; DOI=10.1038/sj.onc.1204611;
RA   Gayet, Jacqueline
RA   Zhou, Xiao-Ping
RA   Duval, Alex
RA   Rolland, Sandra
RA   Hoang, Jean-Marc
RA   Cottu, Paul-Henri
RA   Hamelin, Richard
RT   "Extensive characterization of genetic alterations in a series of
RT   human colorectal cancer cell lines.";
RL   Oncogene 20:5025-5032(2001).
//
RX   PubMed=7329817;
RA   Brattain, Michael G.
RA   Brattain, Diane E.
RA   Fine, W. David
RA   Khaled, F. Mahnaz
RA   Marks, Michael E.
RA   Kimball, Pamela M.
RA   Arcolano, Laurie A.
RA   Danbury, Bernice H.
RT   "Initiation and characterization of cultures of human colonic
RT   carcinoma with different biological characteristics utilizing feeder
RT   layers of confluent fibroblasts.";
RL   Oncodev. Biol. Med. 2:355-366(1981).
//
RX   PubMed=6437669; DOI=10.1007/BF00048384;
RA   Brattain, Michael G.
RA   Levine, Alan E.
RA   Chakrabarty, Subhas
RA   Yeoman, Lynn C.
RA   Willson, James K.V.
RA   Long, Bing
RT   "Heterogeneity of human colon carcinoma.";
RL   Cancer Metastasis Rev. 3:177-191(1984).
//