ID   EB [Human colon carcinoma]
AC   CVCL_F287
SY   HCT-EB; HCT EB
DR   cancercelllines; CVCL_F287
DR   ColonAtlas; EB
DR   Cosmic; 711274
DR   Cosmic; 887228
DR   Cosmic; 889530
DR   Cosmic; 948124
DR   Cosmic; 1057762
DR   GEO; GSM2549998
DR   Wikidata; Q54831736
RX   PubMed=3349466;
RX   PubMed=6437669;
RX   PubMed=7329817;
RX   PubMed=9000147;
RX   PubMed=9000572;
RX   PubMed=11526487;
RX   PubMed=24042735;
RX   PubMed=28683746;
CC   Microsatellite instability: Stable (MSS) (PubMed=9000147; PubMed=24042735; PubMed=28683746).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (PubMed=24042735; PubMed=28683746).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Unspecified (PubMed=24042735; PubMed=28683746).
CC   Omics: Protein expression by reverse-phase protein arrays.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Miscellaneous: STR profile mentioned but not shown in PubMed=24042735; obtained by personal communication of Lind G.E.
CC   Derived from site: In situ; Colon; UBERON=UBERON_0001155.
ST   Source(s): PubMed=24042735
ST   Amelogenin: X
ST   CSF1PO: 12,15
ST   D13S317: 11
ST   D16S539: 11,12
ST   D18S51: 14,16
ST   D19S433: 13
ST   D21S11: 28,32.2
ST   D2S1338: 19
ST   D3S1358: 14,15
ST   D5S818: 10,11
ST   D7S820: 8,9
ST   D8S1179: 11,13
ST   FGA: 21,22.2
ST   TH01: 9,9.3
ST   TPOX: 8,11
ST   vWA: 15,16
DI   NCIt; C4910; Colon carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 05-10-23; Version: 14
//
RX   PubMed=3349466;
RA   Chantret I., Barbat A., Dussaulx E., Brattain M.G., Zweibaum A.;
RT   "Epithelial polarity, villin expression, and enterocytic
RT   differentiation of cultured human colon carcinoma cells: a survey of
RT   twenty cell lines.";
RL   Cancer Res. 48:1936-1942(1988).
//
RX   PubMed=6437669; DOI=10.1007/BF00048384;
RA   Brattain M.G., Levine A.E., Chakrabarty S., Yeoman L.C.,
RA   Willson J.K.V., Long B.;
RT   "Heterogeneity of human colon carcinoma.";
RL   Cancer Metastasis Rev. 3:177-191(1984).
//
RX   PubMed=7329817;
RA   Brattain M.G., Brattain D.E., Fine W.D., Khaled F.M., Marks M.E.,
RA   Kimball P.M., Arcolano L.A., Danbury B.H.;
RT   "Initiation and characterization of cultures of human colonic
RT   carcinoma with different biological characteristics utilizing feeder
RT   layers of confluent fibroblasts.";
RL   Oncodev. Biol. Med. 2:355-366(1981).
//
RX   PubMed=9000147;
RA   Cottu P.-H., Muzeau F., Estreicher A., Flejou J.-F., Iggo R.D.,
RA   Thomas G., Hamelin R.;
RT   "Inverse correlation between RER+ status and p53 mutation in
RT   colorectal cancer cell lines.";
RL   Oncogene 13:2727-2730(1996).
//
RX   PubMed=9000572;
RA   Hoang J.-M., Cottu P.-H., Thuille B., Salmon R.J., Thomas G.,
RA   Hamelin R.;
RT   "BAT-26, an indicator of the replication error phenotype in colorectal
RT   cancers and cell lines.";
RL   Cancer Res. 57:300-303(1997).
//
RX   PubMed=11526487; DOI=10.1038/sj.onc.1204611;
RA   Gayet J., Zhou X.-P., Duval A., Rolland S., Hoang J.-M., Cottu P.-H.,
RA   Hamelin R.;
RT   "Extensive characterization of genetic alterations in a series of
RT   human colorectal cancer cell lines.";
RL   Oncogene 20:5025-5032(2001).
//
RX   PubMed=24042735; DOI=10.1038/oncsis.2013.35;
RA   Ahmed D., Eide P.W., Eilertsen I.A., Danielsen S.A., Eknaes M.,
RA   Hektoen M., Lind G.E., Lothe R.A.;
RT   "Epigenetic and genetic features of 24 colon cancer cell lines.";
RL   Oncogenesis 2:e71.1-e71.8(2013).
//
RX   PubMed=28683746; DOI=10.1186/s12943-017-0691-y;
RA   Berg K.C.G., Eide P.W., Eilertsen I.A., Johannessen B., Bruun J.,
RA   Danielsen S.A., Bjornslett M., Meza-Zepeda L.A., Eknaes M., Lind G.E.,
RA   Myklebost O., Skotheim R.I., Sveen A., Lothe R.A.;
RT   "Multi-omics of 34 colorectal cancer cell lines -- a resource for
RT   biomedical studies.";
RL   Mol. Cancer 16:116.1-116.16(2017).
//