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Cellosaurus NP2 [Human normal mesothelial cells] (CVCL_F1ZN)

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Cell line name NP2 [Human normal mesothelial cells]
Synonyms NP 2
Accession CVCL_F1ZN
Resource Identification Initiative To cite this cell line use: NP2 [Human normal mesothelial cells] (RRID:CVCL_F1ZN)
Comments Doubling time: ~162 hours (PubMed=37566084).
Derived from site: In situ; Lung, pleura; UBERON=UBERON_0000977.
Cell type: Mesothelial cell; CL=CL_0000077.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_F1ZI (NP2-hTERT+)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Finite cell line
STR profile Source(s): PubMed=25188816; PubMed=37566084

Markers:
AmelogeninX,Y
CSF1PO12,14
D3S135815
D5S81812,13
D7S8209,11
D8S117912,14
D13S3178,11
D16S53911
D18S5114,16
D21S1128,31
FGA22,24
Penta D9,13
Penta E11,16
TPOX8
vWA14,16

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Publications

PubMed=25188816; DOI=10.1164/rccm.201404-0658OC
Karin Schelch, Mir A. Hoda, Thomas Klikovits, Julia Munzker, Bahil Ghanim, Christina Wagner, Tamas Garay, Viktoria Laszlo, Ulrike Setinek, Balazs Dome, Martin Filipits ...Show all 24 authors... , Christine Pirker, Petra Heffeter, Edgar Selzer, Jozsef Tovari, Szilvia Torok, Istvan Kenessey, Klaus Holzmann, Bettina Grasl-Kraupp, Brigitte Marian, Walter Klepetko, Walter Berger, Balazs Hegedus, Michael Grusch; Show fewer authors
Fibroblast growth factor receptor inhibition is active against mesothelioma and synergizes with radio- and chemotherapy.
Am. J. Respir. Crit. Care Med. 190:763-772(2014)

PubMed=37566084; DOI=10.3390/cells12152006; PMCID=PMC10417280
Alexander Ries, Astrid Slany, Christine Pirker, Johanna C. Mader, Doris Mejri, Thomas Mohr, Karin Schelch, Daniela Flehberger, Nadine Maach, Muhammad Hashim, Mir Alireza Hoda ...Show all 17 authors... , Balazs Dome, Georg Krupitza, Walter Berger, Christopher Gerner, Klaus Holzmann, Michael Grusch; Show fewer authors
Primary and hTERT-transduced mesothelioma-associated fibroblasts but not primary or hTERT-transduced mesothelial cells stimulate growth of Human Mesothelioma Cells.
Cells 12:2006-2006(2023)

Entry history
Entry creation31-Mar-2026
Last entry update31-Mar-2026
Version number1