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Cellosaurus NP2-hTERT+ (CVCL_F1ZI)

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Cell line name NP2-hTERT+
Synonyms NP2-hT+; NP2i
Accession CVCL_F1ZI
Resource Identification Initiative To cite this cell line use: NP2-hTERT+ (RRID:CVCL_F1ZI)
Comments Doubling time: ~43 hours (PubMed=37566084).
Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Derived from site: In situ; Lung, pleura; UBERON=UBERON_0000977.
Cell type: Mesothelial cell; CL=CL_0000077.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_F1ZN (NP2 [Human normal mesothelial cells])
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Telomerase immortalized cell line
STR profile Source(s): PubMed=37566084

Markers:
AmelogeninX,Y
CSF1PO12,14
D3S135815
D5S81812,13
D7S8209,11
D8S117912,14
D13S3178,11
D16S53911
D18S5114,16
D21S1128,31
FGA22,24
Penta D9,13
Penta E11,16
TPOX8
vWA14,16

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Publications

PubMed=37566084; DOI=10.3390/cells12152006; PMCID=PMC10417280
Alexander Ries, Astrid Slany, Christine Pirker, Johanna C. Mader, Doris Mejri, Thomas Mohr, Karin Schelch, Daniela Flehberger, Nadine Maach, Muhammad Hashim, Mir Alireza Hoda ...Show all 17 authors... , Balazs Dome, Georg Krupitza, Walter Berger, Christopher Gerner, Klaus Holzmann, Michael Grusch; Show fewer authors
Primary and hTERT-transduced mesothelioma-associated fibroblasts but not primary or hTERT-transduced mesothelial cells stimulate growth of Human Mesothelioma Cells.
Cells 12:2006-2006(2023)

Entry history
Entry creation31-Mar-2026
Last entry update31-Mar-2026
Version number1