Cellosaurus L2G7 (CVCL_F1WT)
| Cell line name | L2G7 |
|---|---|
| Accession | CVCL_F1WT |
| Resource Identification Initiative | To cite this cell line use: L2G7 (RRID:CVCL_F1WT) |
| Comments | Group: Patented cell line. Registration: International Depositary Authority, American Type Culture Collection (ATCC); PTA-5162. Biotechnology: The monoclonal antibody produced by this hybridoma was used to prepare the HuL2G7 humanized (TAK-701) therapeutic antibody investigated as a potential anti-cancer drug that works by binding to HGF to block the c-Met signaling pathway, which is involved in tumor growth, survival, and metastasis. Monoclonal antibody isotype: IgG2a, kappa. Monoclonal antibody target: UniProtKB; P14210; Human HGF. |
| Species of origin | Mus musculus (Mouse) (NCBI Taxonomy: 10090) |
| Hierarchy | Parent: CVCL_3412 (P3X63Ag8U.1) |
| Category | Hybridoma |
| Publications | Patent=US7494650 |
| Entry history | |
| Entry creation | 27-Nov-2025 |
| Last entry update | 27-Nov-2025 |
| Version number | 1 |