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Cellosaurus (CVCL_F1WQ)

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Comments Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00545.
Population: Caucasian.
Characteristics: Was thought to have cancer stem cell-like characteristics as it was thought to be produced by long term treatment of MG-63 with 3-aminobenzamide (3AB), an inhibitor of poly(ADP-ribose) polymerase.
Doubling time: ~22 hours (PubMed=19160414).
Selected for resistance to: ChEBI; CHEBI_64042; 3-aminobenzamide (3AB).
Omics: Transcriptomics; Microarray.
Omics: Variations; Array-based CGH.
Omics: Variations; CNV analysis.
Derived from site: In situ; Pelvis, muscle; UBERON=UBERON_0001325.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61His (c.183A>T); ClinVar=VCV000373003; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Trp (c.742C>T); ClinVar=VCV000012347; Zygosity=Homozygous (from parent cell line).
Disease Embryonal rhabdomyosarcoma (NCIt: C8971)
Embryonal rhabdomyosarcoma (ORDO: Orphanet_99757)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1649 (RD)
Sex of cell Female
Age at sampling 7Y
Category Cancer cell line
STR profile Source(s): Millipore=SCC141

Markers:

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Entry history
Entry creation15-Nov-2017
Last entry update10-Apr-2025
Version number17