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Cellosaurus 9F3.18.5 (CVCL_F1WG)

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Cell line name 9F3.18.5
Synonyms 9F3
Accession CVCL_F1WG
Resource Identification Initiative To cite this cell line use: 9F3.18.5 (RRID:CVCL_F1WG)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); PTA-2917.
Biotechnology: The monoclonal antibody produced by this hybridoma was used to prepare the humanized rontalizumab (9F3v13) therapeutic antibody which was designed to target and block the effects of interferon-alphain patients with autoimmune diseases like systemic lupus erythematosus (SLE).
Monoclonal antibody isotype: Not specified.
Monoclonal antibody target: Human alpha-interferons.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_3412 (P3X63Ag8U.1)
Category Hybridoma
Publications

PubMed=11594789; DOI=10.1006/cyto.2001.0934
Anan Chuntharapai, Jadine Lai, Xiao-Jian Huang, Verna C. Gibbs, Kyung Jin Kim, Leonard G. Presta, Timothy A. Stewart;
Characterization and humanization of a monoclonal antibody that neutralizes human leukocyte interferon: a candidate therapeutic for IDDM and SLE.
Cytokine 15:250-260(2001)

Patent=US8557967
Anan Chuntharapai, Kyung Jin Kim, Leonard G. Presta, Timothy A. Stewart;
Anti-interferon-alpha antibodies.
Patent number US8557967, 15-Oct-2013

Cross-references
Biological sample resources ABCD; ABCD_BG479
Entry history
Entry creation27-Nov-2025
Last entry update27-Nov-2025
Version number1