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Cellosaurus HyCyte NCI-N87 KO-hDKK1 (CVCL_F1SC)

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Cell line name HyCyte NCI-N87 KO-hDKK1
Synonyms hDKK1 knockout NCI-N87
Accession CVCL_F1SC
Resource Identification Initiative To cite this cell line use: HyCyte NCI-N87 KO-hDKK1 (RRID:CVCL_F1SC)
Comments Doubling time: 48-60 hours (Hysigen=CGKO-M2814).
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:2891; DKK1.
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Gene deletion; HGNC; HGNC:6770; SMAD4; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:3431; ERBB3; Simple; p.Thr757Lys (c.2270C>A); Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
Disease Gastric tubular adenocarcinoma (NCIt: C5473)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1603 (NCI-N87)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; CGKO-M2814
Entry history
Entry creation27-Nov-2025
Last entry update27-Nov-2025
Version number1