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Cellosaurus HyCyte MDA-MB-436 KO-hARTN (CVCL_F1RT)

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Cell line name HyCyte MDA-MB-436 KO-hARTN
Synonyms hARTN knockout MDA-MB-436
Accession CVCL_F1RT
Resource Identification Initiative To cite this cell line use: HyCyte MDA-MB-436 KO-hARTN (RRID:CVCL_F1RT)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Population: Caucasian.
Doubling time: 60-72 hours (Hysigen=CGKO-M3186).
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:727; ARTN.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:1100; BRCA1; Simple; c.5277+1G>A; ClinVar=VCV000037654; Zygosity=Hemizygous; Note=Splice donor mutation (from parent cell line).
  • Mutation; HGNC; HGNC:9884; RB1; Simple; p.Gly203fs*9 (c.607_608ins227); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu204fs*7 (c.610_612delinsGCGTGTGG); Zygosity=Unspecified (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0623 (MDA-MB-436)
Sex of cell Female
Age at sampling 43Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; CGKO-M3186
Entry history
Entry creation27-Nov-2025
Last entry update27-Nov-2025
Version number1