ID   HyCyte MDA-MB-436 KO-hARTN
AC   CVCL_F1RT
SY   hARTN knockout MDA-MB-436
DR   Hysigen; CGKO-M3186
CC   Group: Triple negative breast cancer (TNBC) cell line.
CC   Population: Caucasian.
CC   Doubling time: 60-72 hours (Hysigen=CGKO-M3186).
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:727; ARTN.
CC   Sequence variation: Mutation; HGNC; HGNC:1100; BRCA1; Simple; c.5277+1G>A; ClinVar=VCV000037654; Zygosity=Hemizygous; Note=Splice donor mutation (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:9884; RB1; Simple; p.Gly203fs*9 (c.607_608ins227); Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu204fs*7 (c.610_612delinsGCGTGTGG); Zygosity=Unspecified (from parent cell line).
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0623 ! MDA-MB-436
SX   Female
AG   43Y
CA   Cancer cell line
DT   Created: 27-11-25; Last updated: 27-11-25; Version: 1
//