Cellosaurus cell line HyCyte LN-229 KO-hAP1S1 (CVCL

Cross-references
Cell line name	HyCyte LN-229 KO-hAP1S1
Synonyms	hAP1S1 knockout LN-229
Accession	CVCL_F1RD
Resource Identification Initiative	To cite this cell line use: HyCyte LN-229 KO-hAP1S1 (RRID:CVCL_F1RD)
Comments	Population: Caucasian. Doubling time: 24-36 hours (Hysigen=CGKO-M2950). Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:559; AP1S1. Derived from site: In situ; Brain, right frontal parieto-occipital cortex.
Sequence variations	Mutation; HGNC; HGNC:6597; LIFR; Simple; p.Pro1060Ala (c.3178C>G); Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:9811; RAD21; Simple; p.Gln132Ter (c.394C>T); Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro98Leu (c.293C>T); ClinVar=VCV000528236; Zygosity=Homozygous (from parent cell line).
Disease	Glioblastoma (NCIt: C3058) Glioblastoma (ORDO: Orphanet_360)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0393 (LN-229)
Sex of cell	Female
Age at sampling	60Y
Category	Cancer cell line
Cell line collections (Providers)	Hysigen; CGKO-M2950
Entry history
Entry creation	27-Nov-2025
Last entry update	27-Nov-2025
Version number	1