Cellosaurus cell line HyCyte Huh-7 KO-hSMARCA4 (CVCL

Cross-references
Cell line name	HyCyte Huh-7 KO-hSMARCA4
Synonyms	hSMARCA4 knockout Huh-7
Accession	CVCL_F1QX
Resource Identification Initiative	To cite this cell line use: HyCyte Huh-7 KO-hSMARCA4 (RRID:CVCL_F1QX)
Comments	Population: Japanese. Doubling time: 36-48 hours (Hysigen=CGKO-M2937). Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:11100; SMARCA4. Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations	Mutation; HGNC; HGNC:6307; KDR; Simple; p.Gln472His (c.1416A>T); ClinVar=VCV000134603; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:20932; POLD3; Simple; p.Lys109Arg (c.326A>G) (p.Lys70Arg, c.209A>G); Zygosity=Unspecified (from parent cell line). Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr220Cys (c.659A>G); ClinVar=VCV000127819; Zygosity=Homozygous (from parent cell line).
Disease	Adult hepatocellular carcinoma (NCIt: C7956) Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0336 (Huh-7)
Sex of cell	Male
Age at sampling	57Y
Category	Cancer cell line
Cell line collections (Providers)	Hysigen; CGKO-M2937
Entry history
Entry creation	27-Nov-2025
Last entry update	27-Nov-2025
Version number	1