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Cellosaurus HyCyte HT-29 KO-hGDF15 (CVCL_F1QS)

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Cell line name HyCyte HT-29 KO-hGDF15
Synonyms hGDF15 knockout HT-29
Accession CVCL_F1QS
Resource Identification Initiative To cite this cell line use: HyCyte HT-29 KO-hGDF15 (RRID:CVCL_F1QS)
Comments Population: Caucasian.
Doubling time: 48-60 hours (Hysigen=CGKO-M3253).
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:30142; GDF15.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Glu853Ter (c.2557G>T); ClinVar=VCV001071632; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1556Asnfs*3 (c.4666dupA) (c.4666_4667insA); ClinVar=VCV000428112; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Pro449Thr (c.1345C>A); ClinVar=VCV001333250; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Gln311Ter (c.931C>T); ClinVar=VCV000230663; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0320 (HT-29)
Sex of cell Female
Age at sampling 44Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; CGKO-M3253
Entry history
Entry creation27-Nov-2025
Last entry update27-Nov-2025
Version number1