Cellosaurus cell line HyCyte HL-60 KO-hARHGDIB (CVCL

Cross-references
Cell line name	HyCyte HL-60 KO-hARHGDIB
Synonyms	hARHGDIB knockout HL-60
Accession	CVCL_F1QM
Resource Identification Initiative	To cite this cell line use: HyCyte HL-60 KO-hARHGDIB (RRID:CVCL_F1QM)
Comments	Population: Caucasian. Doubling time: 24-36 hours (Hysigen=CGKO-M2970). Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:679; ARHGDIB. Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations	Gene deletion; HGNC; HGNC:11998; TP53; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
Disease	Adult acute myeloid leukemia with maturation (NCIt: C7961) Acute myeloblastic leukemia with maturation (ORDO: Orphanet_98834)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0002 (HL-60)
Sex of cell	Female
Age at sampling	36Y
Category	Cancer cell line
Cell line collections (Providers)	Hysigen; CGKO-M2970
Entry history
Entry creation	27-Nov-2025
Last entry update	27-Nov-2025
Version number	1