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Cellosaurus A-172 EMC10 isoform HSS1 (CVCL_F1JP)

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Cell line name A-172 EMC10 isoform HSS1
Synonyms A172 pcDNA3.1-hHSS1
Accession CVCL_F1JP
Resource Identification Initiative To cite this cell line use: A-172 EMC10 isoform HSS1 (RRID:CVCL_F1JP)
Comments Population: Caucasian.
Doubling time: 40 hours (PubMed=20680400).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:27609; EMC10 (Note=Isoform HSS1).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations
  • Gene deletion; HGNC; HGNC:9588; PTEN; Zygosity=Homozygous (from parent cell line).
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1539; CBFB; Name(s)=ABL1-CBFB (from parent cell line).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0131 (A-172)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=20680400; DOI=10.1007/s11060-010-0314-6; PMCID=PMC3052511
Katiana S. Junes-Gill, Timothy K. Gallaher, Zoya Gluzman-Poltorak, Joseph D. Miller, Christopher J. Wheeler, Xue-Mo Fan, Lena A. Basile;
hHSS1: a novel secreted factor and suppressor of glioma growth located at chromosome 19q13.33.
J. Neurooncol. 102:197-211(2011)

Entry history
Entry creation27-Nov-2025
Last entry update27-Nov-2025
Version number1