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Cellosaurus K1735-M2 Elm1.8-3 (CVCL_F0SH)

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Cell line name K1735-M2 Elm1.8-3
Synonyms M-2.Elm1.8-3
Accession CVCL_F0SH
Resource Identification Initiative To cite this cell line use: K1735-M2 Elm1.8-3 (RRID:CVCL_F0SH)
Comments Characteristics: Does not express Ccn4/Elm1 (PubMed=9449709).
Doubling time: 13.1 hours (PubMed=9449709).
Genetic integration: Method=Transfection; Gene=MGI; MGI:1197008; Ccn4.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCIt; C17231; Ultraviolet radiation.
Sequence variations
  • Mutation; MGI; MGI:97376; Nras; Simple; p.Gly13Asp (c.38G>A); Zygosity=Unspecified (from parent cell line).
Disease Mouse melanoma (NCIt: C21790)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H/HeN.
Hierarchy Parent: CVCL_F684 (K1735-M2)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=9449709; DOI=10.1084/jem.187.3.289; PMCID=PMC2212122
Yasunobu Hashimoto, Nobuko Shindo-Okada, Masachika Tani, Yasuhiro Nagamachi, Kaori Takeuchi, Toshihiko Shiroishi, Hiroshi Toma, Jun Yokota;
Expression of the Elm1 gene, a novel gene of the CCN (connective tissue growth factor, Cyr61/Cef10, and neuroblastoma overexpressed gene) family, suppresses In vivo tumor growth and metastasis of K-1735 murine melanoma cells.
J. Exp. Med. 187:289-296(1998)

Entry history
Entry creation27-Nov-2025
Last entry update27-Nov-2025
Version number1