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Cellosaurus NIH 3T3 MCT-1-T81A (CVCL_F0S2)

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Cell line name NIH 3T3 MCT-1-T81A
Accession CVCL_F0S2
Resource Identification Initiative To cite this cell line use: NIH 3T3 MCT-1-T81A (RRID:CVCL_F0S2)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:23357; MCTS1 (Note=With p.Thr81Ala).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: NIH Swiss.
Hierarchy Parent: CVCL_0594 (NIH 3T3)
Sex of cell Male
Age at sampling Embryo
Category Spontaneously immortalized cell line
Publications

PubMed=17016429; DOI=10.1038/sj.onc.1210030
Suvobroto Nandi, Line S. Reinert, Ali B. Hachem, Krystyna Mazan-Mamczarz, Patrick R. Hagner, Hui-Li He, Ronald Benjamin Gartenhaus;
Phosphorylation of MCT-1 by p44/42 MAPK is required for its stabilization in response to DNA damage.
Oncogene 26:2283-2289(2007)

Entry history
Entry creation27-Nov-2025
Last entry update27-Nov-2025
Version number1