Cellosaurus cell line Coala (CVCL

Cellosaurus Coala (CVCL_F0RS)

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Cell line name

Coala

Accession

CVCL_F0RS

Resource Identification Initiative

To cite this cell line use: Coala (RRID:CVCL_F0RS)

Comments

Characteristics: Can also be cultured as a 3D spheroid (PubMed=40758205).
Doubling time: ~2.5 days (PubMed=40758205).
Omics: Genomics; Whole exome sequencing.
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.

Sequence variations

Mutation; HGNC; HGNC:583; APC; Simple; p.Glu1309Aspfs*4 (c.3927_3931delAAAGA); ClinVar=VCV000000816; Zygosity=Heterozygous (PubMed=40758205).
Mutation; HGNC; HGNC:583; APC; Simple; p.Ser1355Leufs*60 (c.4063delT); ClinVar=VCV002121014; Zygosity=Heterozygous (PubMed=40758205).
Mutation; HGNC; HGNC:1100; BRCA1; Simple; p.Lys1183Arg (c.3548A>G); ClinVar=VCV000041818; Zygosity=Heterozygous (PubMed=40758205).
Mutation; HGNC; HGNC:3430; ERBB2; Simple; p.Pro1170Ala (c.3508C>G); ClinVar=VCV000134082; Zygosity=Heterozygous (PubMed=40758205).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Heterozygous (PubMed=40758205).

Disease

Colon adenocarcinoma (NCIt: C4349)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

68Y

Category

Cancer cell line

STR profile

Source(s): PubMed=40758205

Markers:

CSF1PO	10,11
D5S818	10,12
D7S820	10,12
D13S317	8,12
D16S539	14
TH01	6,9
TPOX	8,11
vWA	18,19

Publications

PubMed=40758205; DOI=10.1007/s13577-025-01256-1; PMCID=PMC12321644
Sandra Mersakova, Juraj Marcinek, Dusan Brany, Olga Chodelkova, Martin Vorcak, Martin Cermak, Martina Poturnajova, Zuzana Kozovska, Henrieta Skovierova, Slavomira Novakova, Barbora Mitruskova ...Show all 34 authors... , Dusan Loderer, Marian Grendar, Veronika Holubekova, Andrea Hornakova, Jana Melegova, Mariana Brozmanova, Blazej Palkoci, Martin Vojtko, Roman Kycina, Miroslav Pindura, Jan Janik, Peter Mikolajcik, Eva Gabonova, Ludovit Laca, Andreas Nicodemou, Lubos Danisovic, Lukas Plank, Erika Halasova, Marek Mraz, Miroslava Matuskova, Zora Lasabova, Michal Kalman, Jan Strnadel; Show fewer authors
Establishment of Coala: a novel 3D and 2D cancer cell line derived from colorectal cancer liver metastasis.
Hum. Cell 38:137.1-137.16(2025)

Entry history

Entry creation

27-Nov-2025

Last entry update

27-Nov-2025

Version number