ID   Coala
AC   CVCL_F0RS
RX   PubMed=40758205;
CC   Characteristics: Can also be cultured as a 3D spheroid (PubMed=40758205).
CC   Doubling time: ~2.5 days (PubMed=40758205).
CC   Sequence variation: Mutation; HGNC; HGNC:583; APC; Simple; p.Glu1309Aspfs*4 (c.3927_3931delAAAGA); ClinVar=VCV000000816; Zygosity=Heterozygous (PubMed=40758205).
CC   Sequence variation: Mutation; HGNC; HGNC:583; APC; Simple; p.Ser1355Leufs*60 (c.4063delT); ClinVar=VCV002121014; Zygosity=Heterozygous (PubMed=40758205).
CC   Sequence variation: Mutation; HGNC; HGNC:1100; BRCA1; Simple; p.Lys1183Arg (c.3548A>G); ClinVar=VCV000041818; Zygosity=Heterozygous (PubMed=40758205).
CC   Sequence variation: Mutation; HGNC; HGNC:3430; ERBB2; Simple; p.Pro1170Ala (c.3508C>G); ClinVar=VCV000134082; Zygosity=Heterozygous (PubMed=40758205).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Heterozygous (PubMed=40758205).
CC   Omics: Genomics; Whole exome sequencing.
CC   Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
ST   Source(s): PubMed=40758205
ST   CSF1PO: 10,11
ST   D13S317: 8,12
ST   D16S539: 14
ST   D5S818: 10,12
ST   D7S820: 10,12
ST   TH01: 6,9
ST   TPOX: 8,11
ST   vWA: 18,19
DI   NCIt; C4349; Colon adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   68Y
CA   Cancer cell line
DT   Created: 27-11-25; Last updated: 27-11-25; Version: 1
//
RX   PubMed=40758205; DOI=10.1007/s13577-025-01256-1; PMCID=PMC12321644;
RA   Mersakova, Sandra
RA   Marcinek, Juraj
RA   Brany, Dusan
RA   Chodelkova, Olga
RA   Vorcak, Martin
RA   Cermak, Martin
RA   Poturnajova, Martina
RA   Kozovska, Zuzana
RA   Skovierova, Henrieta
RA   Novakova, Slavomira
RA   Mitruskova, Barbora
RA   Loderer, Dusan
RA   Grendar, Marian
RA   Holubekova, Veronika
RA   Hornakova, Andrea
RA   Melegova, Jana
RA   Brozmanova, Mariana
RA   Palkoci, Blazej
RA   Vojtko, Martin
RA   Kycina, Roman
RA   Pindura, Miroslav
RA   Janik, Jan
RA   Mikolajcik, Peter
RA   Gabonova, Eva
RA   Laca, Ludovit
RA   Nicodemou, Andreas
RA   Danisovic, Lubos
RA   Plank, Lukas
RA   Halasova, Erika
RA   Mraz, Marek
RA   Matuskova, Miroslava
RA   Lasabova, Zora
RA   Kalman, Michal
RA   Strnadel, Jan
RT   "Establishment of Coala: a novel 3D and 2D cancer cell line derived
RT   from colorectal cancer liver metastasis.";
RL   Hum. Cell 38:137.1-137.16(2025).
//