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Cellosaurus AGS-2 (CVCL_F0QP)

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Cell line name AGS-2
Accession CVCL_F0QP
Resource Identification Initiative To cite this cell line use: AGS-2 (RRID:CVCL_F0QP)
Comments Population: Caucasian.
Doubling time: 37 hours (PubMed=6831414).
Derived from site: In situ; Stomach; UBERON=UBERON_0000945.
Sequence variations
  • Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Gly34Glu (c.101G>A); ClinVar=VCV000017584; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu453Lys (c.1357G>A); ClinVar=VCV000376470; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Ala (c.1634A>C); ClinVar=VCV000013659; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:667; RHOA; Simple; p.Glu64del (c.192_194del); Zygosity=Heterozygous (from parent cell line).
Disease Gastric adenocarcinoma (NCIt: C4004)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0139 (AGS)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line
Publications

PubMed=6831414
Sam Christopher Barranco, Courtney M. Townsend Jr., Cacilda Casartelli, Barbara Gail Macik, N.L. Burger, William Robert Boerwinkle, William Kneff Gourley;
Establishment and characterization of an in vitro model system for human adenocarcinoma of the stomach.
Cancer Res. 43:1703-1709(1983)

Entry history
Entry creation27-Nov-2025
Last entry update27-Nov-2025
Version number1