Cellosaurus logo
expasy logo

Cellosaurus U2OS-RFP-GAL3 (CVCL_F0QJ)

[Text][XML][JSON]
Cell line name U2OS-RFP-GAL3
Accession CVCL_F0QJ
Resource Identification Initiative To cite this cell line use: U2OS-RFP-GAL3 (RRID:CVCL_F0QJ)
Comments Population: Caucasian.
Characteristics: Transfected with a pmRFP-C1-Galectin-3 construct (DOI=10.1101/2023.09.11.557213).
Genetic integration: Method=Transfection; Gene=FPbase; 5YCFA; mRFP1 (Note=Bright red fluorescent protein derived from drFP583 (DsRed)).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:6563; LGALS3.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Sequence variations
  • Mutation; HGNC; HGNC:9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0042 (U2OS)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
Publications

DOI=10.1101/2023.09.11.557213
Mai Nguyen, Jack J. Collier, Olesia Ignatenko, Genevieve Morin, Si-Dong Huang, Michel Desjardins, Heidi M. McBride;
Parkinson's genes orchestrate pyroptosis through selective trafficking of mtDNA to leaky lysosomes.
bioRxiv 2023:09.11.557213-09.11.557213(2023)

Entry history
Entry creation27-Nov-2025
Last entry update27-Nov-2025
Version number1