ID   U2OS-RFP-GAL3
AC   CVCL_F0QJ
RX   DOI=10.1101/2023.09.11.557213;
CC   Population: Caucasian.
CC   Characteristics: Transfected with a pmRFP-C1-Galectin-3 construct (DOI=10.1101/2023.09.11.557213).
CC   Sequence variation: Mutation; HGNC; HGNC:9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=FPbase; 5YCFA; mRFP1 (Note=Bright red fluorescent protein derived from drFP583 (DsRed)).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:6563; LGALS3.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
DI   NCIt; C9145; Osteosarcoma
DI   ORDO; Orphanet_668; Osteosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0042 ! U2OS
SX   Female
AG   15Y
CA   Cancer cell line
DT   Created: 27-11-25; Last updated: 27-11-25; Version: 1
//
RX   DOI=10.1101/2023.09.11.557213;
RA   Nguyen, Mai
RA   Collier, Jack J.
RA   Ignatenko, Olesia
RA   Morin, Genevieve
RA   Huang, Si-Dong
RA   Desjardins, Michel
RA   McBride, Heidi M.
RT   "Parkinson's genes orchestrate pyroptosis through selective
RT   trafficking of mtDNA to leaky lysosomes.";
RL   bioRxiv 2023:09.11.557213-09.11.557213(2023).
//