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Cellosaurus WI38-hTERT-E6-E7 (CVCL_F0KE)

[Text version]
Cell line name WI38-hTERT-E6-E7
Accession CVCL_F0KE
Resource Identification Initiative To cite this cell line use: WI38-hTERT-E6-E7 (RRID:CVCL_F0KE)
Comments Population: Caucasian; Swedish.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Fetal lung; UBERON=UBERON_0005597.
Cell type: Fibroblast of lung; CL=CL_0002553.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0579 (WI-38)
Sex of cell Female
Age at sampling 16FW
Category Transformed cell line
Publications

PubMed=24413054; DOI=10.1038/nsmb.2754; PMCID=PMC3946341
Roderick J. O'Sullivan, Nausica Arnoult, Daniel H. Lackner, Liana Oganesian, Candy I. Haggblom, Armelle Corpet, Genevieve Almouzni, Jan Karlseder;
Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1.
Nat. Struct. Mol. Biol. 21:167-174(2014)

Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1