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Cellosaurus HeLa LT [2014] (CVCL_F0J8)

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Cell line name HeLa LT [2014]
Synonyms HeLa Long Telomere
Accession CVCL_F0J8
Resource Identification Initiative To cite this cell line use: HeLa LT [2014] (RRID:CVCL_F0J8)
Comments Population: African American.
Characteristics: Has long telomeres (~20 kb) (PubMed=24413054).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B5D9 (HeLa1.2.11)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Publications

PubMed=24413054; DOI=10.1038/nsmb.2754; PMCID=PMC3946341
Roderick J. O'Sullivan, Nausica Arnoult, Daniel H. Lackner, Liana Oganesian, Candy I. Haggblom, Armelle Corpet, Genevieve Almouzni, Jan Karlseder;
Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1.
Nat. Struct. Mol. Biol. 21:167-174(2014)

PubMed=38213617; DOI=10.1016/j.isci.2023.108655; PMCID=PMC10783591
Robert Lu, Christopher B. Nelson, Samuel Rogers, Anthony J. Cesare, Alexander Peter Sobinoff, Hilda A. Pickett;
Distinct modes of telomere synthesis and extension contribute to alternative lengthening of telomeres.
iScience 27:108655.1-108655.21(2024)

Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1