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Cellosaurus HeLa1.2.11 (CVCL_B5D9)

[Text version]
Cell line name HeLa1.2.11
Synonyms HeLa 1.2.11
Accession CVCL_B5D9
Resource Identification Initiative To cite this cell line use: HeLa1.2.11 (RRID:CVCL_B5D9)
Comments Population: African American.
Characteristics: Has exceptionally long telomeres of approximately 23 kb in length (PubMed=10338214).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Caution: The second allele values for D13S317 is incorrectly indicated as 13.5 in PubMed=19864690 (personal communication of de Lange, Titia through Korch, Christopher T.).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B5D4 (HeLaI)
Children:
CVCL_F0J8 (HeLa LT [2014])CVCL_F0J9 (HeLa ST)CVCL_F0JA (HeLa VST)
CVCL_B5DA (HeLa1.3)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): PubMed=19864690

Markers:
AmelogeninX
CSF1PO9,10
D2S133817
D3S135815,18
D5S81811,12
D8S117912,13
D13S31712,13.3
D16S5399,10
D18S5116
D19S43313,14
D21S1127,28
FGA18,21
TH017
TPOX8,12
vWA16,18

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Publications

PubMed=9476899; DOI=10.1016/S0092-8674(00)80932-0
Bas van Steensel, Agata Smogorzewska, Titia de Lange;
TRF2 protects human telomeres from end-to-end fusions.
Cell 92:401-413(1998)

PubMed=10338214; DOI=10.1016/S0092-8674(00)80760-6
Jack D. Griffith, Laurey Comeau, Soraya Rosenfield, Rachel M. Stansel, Alessandro Bianchi, Heidi Moss, Titia de Lange;
Mammalian telomeres end in a large duplex loop.
Cell 97:503-514(1999)

PubMed=19864690; DOI=10.1074/jbc.M109.038026; PMCID=PMC2801271
Kaori K. Takai, Sarah Hooper, Stephanie Blackwood, Rita Gandhi, Titia de Lange;
In vivo stoichiometry of shelterin components.
J. Biol. Chem. 285:1457-1467(2010)

PubMed=24413054; DOI=10.1038/nsmb.2754; PMCID=PMC3946341
Roderick J. O'Sullivan, Nausica Arnoult, Daniel H. Lackner, Liana Oganesian, Candy I. Haggblom, Armelle Corpet, Genevieve Almouzni, Jan Karlseder;
Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1.
Nat. Struct. Mol. Biol. 21:167-174(2014)

Cross-references
Cell line databases/resources TOKU-E; 3894
Encyclopedic resources Wikidata; Q110432882
Entry history
Entry creation16-Dec-2021
Last entry update14-Aug-2025
Version number7