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Cellosaurus HTR8/SVneo/HRASV12 (CVCL_F0D7)

[Text version]
Cell line name HTR8/SVneo/HRASV12
Accession CVCL_F0D7
Resource Identification Initiative To cite this cell line use: HTR8/SVneo/HRASV12 (RRID:CVCL_F0D7)
Comments Characteristics: Transduced with a pMX-HRASV12-IRES-EGFP construct (PubMed=21787741).
Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSV3-neo).
Derived from site: In situ; Trophoblast; UBERON=UBERON_0000088.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_7162 (HTR-8/SVneo)
Children:
CVCL_M689 (iC(3)-1)
Sex of cell Sex unspecified
Age at sampling 6-12FW
Category Transformed cell line
Publications

PubMed=21787741; DOI=10.1016/j.ajpath.2011.05.019; PMCID=PMC3157189
Yusuke Kobayashi, Takatsune Shimizu, Hideaki Naoe, Arisa Ueki, Joe Ishizawa, Tatsuyuki Chiyoda, Nobuyuki Onishi, Eiji Sugihara, Osamu Nagano, Kouji Banno, Shinji Kuninaka ...Show all 13 authors... , Daisuke Aoki, Hideyuki Saya; Show fewer authors
Establishment of a choriocarcinoma model from immortalized normal extravillous trophoblast cells transduced with HRASV12.
Am. J. Pathol. 179:1471-1482(2011)

Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1