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Cellosaurus iVMP C1 (CVCL_F0D2)

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Cell line name iVMP C1
Synonyms immortalized VM Precursor clone C1; C1
Accession CVCL_F0D2
Resource Identification Initiative To cite this cell line use: iVMP C1 (RRID:CVCL_F0D2)
Comments Doubling time: 18.3 hours (PubMed=20177706).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen (Note=With p.Leu156_Thr708del = T155g).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSV3-neo).
Derived from site: In situ; Embryonic brain, ventral mesencephalon; UBERON=UBERON_0001943.
Cell type: Neural progenitor cell; CL=CL_0011020.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Sprague Dawley; RS=RS_0000681.
Originate from same individual CVCL_F0D3 ! iVMP C2
CVCL_F0D4 ! iVMP C3
CVCL_F0D5 ! iVMP C4
Sex of cell Sex unspecified
Age at sampling 12FD
Category Transformed cell line
Publications

PubMed=20177706; DOI=10.1007/s00441-010-0933-4
Andre Nobre, Ieva Kalve, Konstantin Cesnulevicius, Daniela Ragancokova, Andreas Ratzka, Nina Halfer, Maike Wesemann, Klaus Krampfl, Peter Claus, Claudia Grothe;
Characterization and differentiation potential of rat ventral mesencephalic neuronal progenitor cells immortalized with SV40 large T antigen.
Cell Tissue Res. 340:29-43(2010)

PubMed=22863662; DOI=10.1111/j.1582-4934.2012.01607.x; PMCID=PMC4118228
Asir Alwin Prem Anand, S. Gowri Sankar, Kokila V. Vani;
Immortalization of neuronal progenitors using SV40 large T antigen and differentiation towards dopaminergic neurons.
J. Cell. Mol. Med. 16:2592-2610(2012)

Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1